WTIP antibody (C-Term)

Catalog No. ABIN955587

The Rabbit Polyclonal anti-WTIP antibody (ABIN955587) specifically detects WTIP in WB, IF, IHC (p) and EIA. The antibody is reactive with Human samples.

Quick Overview for WTIP antibody (C-Term) (ABIN955587)

Target: WTIP (Wilms Tumor 1 Interacting Protein (WTIP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WTIP antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-WTIP Antibody

Binding Specificity: AA 474-503, C-Term

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 474-503 amino acids from the C-terminal region of human WTIP

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for WTIP

Target: WTIP (Wilms Tumor 1 Interacting Protein (WTIP))

Alternative Name: WTIP

Background: WTIP may monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes. In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator that represses WT1-dependent transcription regulation, thereby translating changes in slit diaphragm structure into altered gene expression and a less differentiated phenotype (By similarity).Synonyms: Wilms tumor protein 1-interacting protein

Gene ID: 9606