DFNB31 antibody (Middle Region)

Catalog No. ABIN955575

Product Details anti-DFNB31 Antibody

Target: DFNB31 (Deafness, Autosomal Recessive 31 (DFNB31))

Binding Specificity: AA 385-413, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DFNB31 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human Whirlin (Center).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 385-413 amino acids from the Central region of Human Whirlin. Genename: WHRN

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for DFNB31

Target: DFNB31 (Deafness, Autosomal Recessive 31 (DFNB31))

Alternative Name: Whirlin (DFNB31 Products)

Synonyms: DFNB31 antibody, CIP98 antibody, PDZD7B antibody, USH2D antibody, WHRN antibody, WI antibody, Cip98 antibody, Whrn antibody, 1110035G07Rik antibody, AW122018 antibody, AW742671 antibody, C430046P22Rik antibody, Dfnb31 antibody, wi antibody, whirlin antibody, WHRN antibody, LOC100555508 antibody, Whrn antibody

Background: This gene is thought to function in the organization and stabilization of sterocilia elongation and actin cystoskeletal assembly, based on studies of the related mouse gene. Mutations in this gene have been associated with autosomal recessive non-syndromic deafness and Usher Syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.Synonyms: Autosomal recessive deafness type 31 protein, DFNB31, KIAA1526, WHRN

Molecular Weight: 96586 Da

Gene ID: 25861

NCBI Accession: NP_001077354

Pathways: Sensory Perception of Sound