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RENT2/UPF2 antibody (Middle Region)
UPF2
Reactivity: Human
WB, FACS, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-RENT2/UPF2 Antibody
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Target
See all RENT2/UPF2 (UPF2) Antibodies
RENT2/UPF2 (UPF2)
(UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
Binding Specificity
All epitopes for RENT2/UPF2 antibodies
AA 633-660, Middle Region
Reactivity
All reactivities for RENT2/UPF2 antibodies
Human
Host
All hosts for RENT2/UPF2 antibodies
Rabbit
Clonality
All clonalities for RENT2/UPF2 antibodies
Polyclonal
Conjugate
All conjugates for RENT2/UPF2 antibodies
This RENT2/UPF2 antibody is un-conjugated
Application
All applications for RENT2/UPF2 antibodies
Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
Specificity
This antibody detects UPF2 / RENT2 (Center).
Cross-Reactivity (Details)
Species reactivity (tested):Human
Purification
Protein A column followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 633-660 amino acids from the Central region of human UPF2
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Target Details for RENT2/UPF2
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Target
RENT2/UPF2 (UPF2)
(UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
Alternative Name
UPF2 / RENT2 (UPF2 Products )
Synonyms
HUPF2 antibody, RENT2 antibody, smg-3 antibody, UPF2, regulator of nonsense mediated mRNA decay antibody, UPF2 regulator of nonsense transcripts homolog (yeast) antibody, UPF2 antibody, Upf2 antibody, upf2 antibody
Background
UPF2 is a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p.Synonyms: KIAA1408, Regulator of nonsense transcripts 2, Up-frameshift suppressor 2 homolog
Gene ID
26019
NCBI Accession
NP_056357
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