STARD6 antibody (C-Term)

Catalog No. ABIN954974

The Rabbit Polyclonal anti-STARD6 antibody has been validated for WB and EIA. It is suitable to detect STARD6 in samples from Human.

Quick Overview for STARD6 antibody (C-Term) (ABIN954974)

Target: STARD6 (StAR-Related Lipid Transfer (START) Domain Containing 6 (STARD6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STARD6 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-STARD6 Antibody

Binding Specificity: AA 194-220, C-Term

Specificity: This antibody recognizes Human (C-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 194-220 amino acids from the C-terminal region of Human STARD6

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for STARD6

Target: STARD6 (StAR-Related Lipid Transfer (START) Domain Containing 6 (STARD6))

Alternative Name: STARD6

Background: Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1, MIM 184756) and by liver X receptors (e.g., LXRA, MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR, MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD6 (Soccio et al., 2002 [PubMed 12011452])Synonyms: START domain-containing protein 6, StAR-related lipid transfer protein 6

Molecular Weight: 25022 Da

Gene ID: 147323

NCBI Accession: NP_631910