SPRR1B antibody (C-Term)

Catalog No. ABIN954942

Product Details anti-SPRR1B Antibody

Target: SPRR1B (Small Proline Rich Protein 1B (SPRR1B))

Binding Specificity: AA 60-89, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPRR1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes SPRR1B / Cornifin-B at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 60-89aa) of human SPRR1B / Cornifin-B

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SPRR1B

Target: SPRR1B (Small Proline Rich Protein 1B (SPRR1B))

Alternative Name: SPRR1B / Cornifin-B (SPRR1B Products)

Synonyms: CORNIFIN antibody, GADD33 antibody, SPRR1 antibody, SPRR1B antibody, small proline rich protein 1B antibody, small proline-rich protein antibody, small proline-rich protein 1B antibody, SPRR1B antibody, SPRP antibody, Sprr1b antibody

Background: SPRR1B/Cornifin-B is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Cornifin-B can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.Synonyms: SPR-IB, Small proline-rich protein IB

Gene ID: 6699

NCBI Accession: NP_003116