SPACA1 antibody (N-Term)

Catalog No. ABIN954901

Product Details anti-SPACA1 Antibody

Target: SPACA1 (Sperm Acrosome Associated 1 (SPACA1))

Binding Specificity: AA 49-78, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPACA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: Recognizes SACA1 (N-term).

Purification: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 49-78 amino acids from the N-terminal region of Human SACA1 Genename: SPACA1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SPACA1

Target: SPACA1 (Sperm Acrosome Associated 1 (SPACA1))

Alternative Name: SPACA1 / SAMP32 (SPACA1 Products)

Synonyms: SAMP32 antibody, 1700124L11Rik antibody, 4930540L03Rik antibody, sperm acrosome associated 1 antibody, SPACA1 antibody, Spaca1 antibody

Background: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.Synonyms: Sperm acrosomal membrane-associated protein 32, Sperm acrosome membrane-associated protein 1

Gene ID: 81833

NCBI Accession: NP_112222