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FAM33A antibody (N-Term)
FAM33A
Reactivity: Human
WB, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-FAM33A Antibody
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Target
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FAM33A
(Spindle and Kinetochore-Associated Protein 2 (FAM33A))
Binding Specificity
All epitopes for FAM33A antibodies
AA 16-45, N-Term
Reactivity
All reactivities for FAM33A antibodies
Human
Host
All hosts for FAM33A antibodies
Rabbit
Clonality
All clonalities for FAM33A antibodies
Polyclonal
Conjugate
All conjugates for FAM33A antibodies
This FAM33A antibody is un-conjugated
Application
All applications for FAM33A antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human SKA2 (N-term).
Purification
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 16-45 amino acids from the N-terminal region of Human SKA2 Genename: SKA2
Isotype
Ig Fraction
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Discover our top product FAM33A Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for FAM33A
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Target
FAM33A
(Spindle and Kinetochore-Associated Protein 2 (FAM33A))
Alternative Name
SKA2 (FAM33A Products )
Synonyms
FAM33A antibody, 1110001A07Rik antibody, C78640 antibody, Fam33a antibody, RGD1307084 antibody, fam33a antibody, spindle and kinetochore associated complex subunit 2 antibody, Spindle and kinetochore-associated protein 2 antibody, SKA2 antibody, Ska2 antibody, ska2 antibody
Background
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it is required for SKA1 localization.Synonyms: FAM33A, Spindle and kinetochore-associated protein 2
Molecular Weight
14188 Da
Gene ID
348235
NCBI Accession
NP_872426
Pathways
M Phase
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