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SPR antibody (C-Term)
SPR
Reactivity: Human, Mouse
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SPR Antibody
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Target
See all SPR Antibodies
SPR
(Sepiapterin Reductase (SPR))
Binding Specificity
All epitopes for SPR antibodies
AA 232-261, C-Term
Reactivity
All reactivities for SPR antibodies
Human, Mouse
Host
All hosts for SPR antibodies
Rabbit
Clonality
All clonalities for SPR antibodies
Polyclonal
Conjugate
All conjugates for SPR antibodies
This SPR antibody is un-conjugated
Application
All applications for SPR antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Sepiapterin reductase / SPRat N-term.
Cross-Reactivity (Details)
Species reactivity (tested):Human, Mouse
Purification
Purified through a Protein A column followed by peptide affinity purification
Immunogen
Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 232-261aa) of human Sepiapterin reductase / SPR.
Isotype
Ig Fraction
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Discover our top product SPR Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for SPR
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Target
SPR
(Sepiapterin Reductase (SPR))
Alternative Name
Sepiapterin Reductase / SPR (SPR Products )
Synonyms
SDR38C1 antibody, AA409688 antibody, ENSMUSG00000071345 antibody, Gm10328 antibody, CG12117 antibody, Dmel\\CG12117 antibody, SR antibody, sptr antibody, xspr antibody, DDBDRAFT_0188686 antibody, DDBDRAFT_0191275 antibody, DDB_0188686 antibody, DDB_0191275 antibody, zgc:194446 antibody, sepiapterin reductase antibody, Sepiapterin reductase antibody, sepiapterin reductase L homeolog antibody, sepiapterin reductase b antibody, SPR antibody, Spr antibody, Sptr antibody, spr.L antibody, sprE antibody, CpipJ_CPIJ000511 antibody, sr antibody, spr antibody, sprb antibody
Background
The SPR gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiapterin reductase deficiency. A pseudogene has been identified on chromosome 1.Synonyms: EC 1.1.1.153, SDR38C1, short chain dehydrogenase/reductase family 38C member 1
Gene ID
6697
NCBI Accession
NP_003115
Pathways
Regulation of Systemic Arterial Blood Pressure by Hormones , Feeding Behaviour , Smooth Muscle Cell Migration
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