SEC62 antibody (N-Term)

Catalog No. ABIN954706

Product Details anti-SEC62 Antibody

Target: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Binding Specificity: AA 1-30, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC62 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: Recognizes SEC62 (N-term).

Purification: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of Human SEC62 Genename: SEC62

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SEC62

Target: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Alternative Name: SEC62 / TLOC1 (TLOC1 Products)

Synonyms: tloc1 antibody, TLOC1 antibody, wu:fb57b06 antibody, zgc:114073 antibody, Dtrp1 antibody, HTP1 antibody, TP-1 antibody, 3100002M17Rik antibody, AI844545 antibody, AW545092 antibody, Tloc1 antibody, Ab2-292 antibody, SEC62 homolog, preprotein translocation factor S homeolog antibody, SEC62 homolog, preprotein translocation factor antibody, membrane unit of ER protein translocation apparatus antibody, SEC62 homolog (S. cerevisiae) antibody, sec62.S antibody, SEC62 antibody, sec62 antibody, Sec62 antibody

Background: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.Synonyms: Translocation protein 1, Translocation protein SEC62

Gene ID: 7095

NCBI Accession: NP_003253