RUSC2 antibody (N-Term)

Catalog No. ABIN954645

Product Details anti-RUSC2 Antibody

Target: RUSC2 (RUN and SH3 Domain Containing 2 (RUSC2))

Binding Specificity: AA 315-344, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUSC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: Recognizes RUSC2 (N-term).

Purification: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 315-344 amino acids from the N-terminal region of Human RUSC2 Genename: RUSC2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for RUSC2

Target: RUSC2 (RUN and SH3 Domain Containing 2 (RUSC2))

Alternative Name: RUSC2 (RUSC2 Products)

Synonyms: MGC142511 antibody, DKFZp469H2039 antibody, Iporin antibody, AI840675 antibody, mKIAA0375 antibody, RUN and SH3 domain containing 2 antibody, RUSC2 antibody, rusc2 antibody, Rusc2 antibody

Background: RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30 % amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions.Synonyms: Interacting protein of Rab1, Iporin, KIAA0375, RUN and SH3 domain-containing protein 2

Gene ID: 9853

NCBI Accession: NP_001129471