RBBP7 antibody (Middle Region)

Catalog No. ABIN954472

Product Details anti-RBBP7 Antibody

Target: RBBP7 (Retinoblastoma Binding Protein 7 (RBBP7))

Binding Specificity: AA 190-219, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBBP7 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human RBBP7 (Center).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 190-219 amino acids from the Central region of Human RBBP7. Genename: RBBP7

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for RBBP7

Target: RBBP7 (Retinoblastoma Binding Protein 7 (RBBP7))

Alternative Name: RBBP7 / RBAP46 (RBBP7 Products)

Background: This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.Synonyms: Histone-binding protein RBBP7, Nucleosome-remodeling factor subunit RBAP46, RBBP-7, Retinoblastoma-binding protein 7, Retinoblastoma-binding protein p46

Molecular Weight: 47820 Da

Gene ID: 5931

NCBI Accession: NP_002884