HR54 antibody, RAD54A antibody, hHR54 antibody, hRAD54 antibody, RAD54 antibody, zgc:56289 antibody, rad54l antibody, MGC69368 antibody, GdRAD54 antibody, RAD54-like antibody, RAD54L antibody, RAD54 like antibody, RAD54 like (S. cerevisiae) antibody, RAD54-like (S. cerevisiae) antibody, RAD54L antibody, Rad54l antibody, rad54l antibody
Background
The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.Synonyms: DNA repair and recombination protein RAD54-like, RAD54 homolog, RAD54A, hHR54, hRAD54