PTTG1IP antibody (Internal Region)

Catalog No. ABIN954383

Product Details anti-PTTG1IP Antibody

Target: PTTG1IP (Pituitary Tumor-Transforming 1 Interacting Protein (PTTG1IP))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTTG1IP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects endogenous levels of total PTTG protein.

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide from Human PTTG. Epitope: Internal.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PTTG1IP

Target: PTTG1IP (Pituitary Tumor-Transforming 1 Interacting Protein (PTTG1IP))

Alternative Name: PTTG1IP (PTTG1IP Products)

Background: The encoded protein, which directly binds to pituitary tumor-transforming protein-1 (PTTG1), facilitates the nuclear translocation of PTTG1 and potentiates the transcriptional activation of basic fibroblast growth factor by PTTG1. The gene product localizes to both the cytoplasm and nucleus. Its NLS is required for its own nuclear localization, the nuclear localization of PTTG1, and its interaction with PTTG1.Synonyms: C21orf1, C21orf3, PBF, PTTG-binding factor, Pituitary tumor-transforming gene 1 protein-interacting protein, Pituitary tumor-transforming gene protein-binding factor

Gene ID: 754

NCBI Accession: NP_004330

Pathways: Protein targeting to Nucleus