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PRUNE antibody

PRUNE Reactivity: Human WB, IHC (p), EIA Host: Mouse Monoclonal 1C11 unconjugated
Catalog No. ABIN954343
  • Target See all PRUNE Antibodies
    PRUNE (Prune Exopolyphosphatase (PRUNE))
    Reactivity
    • 36
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 46
    • 5
    Mouse
    Clonality
    • 48
    • 3
    Monoclonal
    Conjugate
    • 17
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRUNE antibody is un-conjugated
    Application
    • 39
    • 24
    • 16
    • 13
    • 13
    • 13
    • 6
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes PRUNE
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Protein A Chromatography
    Immunogen
    Recombinant protein.
    Clone
    1C11
    Isotype
    IgG2a
    Top Product
    Discover our top product PRUNE Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.2
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    PRUNE (Prune Exopolyphosphatase (PRUNE))
    Alternative Name
    PRUNE (PRUNE Products)
    Synonyms
    PRUNE antibody, DRES-17 antibody, DRES17 antibody, HTCD37 antibody, 9230112O05Rik antibody, C130058A12 antibody, PRUNEM1 antibody, Prune-M1 antibody, prune exopolyphosphatase antibody, prune exopolyphosphatase 1 antibody, PRUNE1 antibody, Prune1 antibody
    Background
    PRUNE, the human homologue of the Drosophila gene, is located in 1q21.3, a region highly amplified in human sarcomas, malignant tumours of mesenchymal origin. Human prune (h-prune), a phosphoesterase DHH family appertaining protein, physically interacts with nm23-H1, a metastasis suppressor gene. h-prune is involved in cellular motility and metastasis formation. Metastatic breast cancers were found to overexpress h-prune, h-prune was also found to be highly expressed in colorectal and pancreatic cancers. Hence h-prune is considered useful as a marker for tumor aggressiveness.Synonyms: DRES-17, DRES17, Drosophila-related expressed sequence 17, HTcD37, Protein prune homolog, hPrune
    Gene ID
    58497
    NCBI Accession
    NP_067045
    UniProt
    Q86TP1
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