PPP1R14C antibody (C-Term)

Catalog No. ABIN954270

Product Details anti-PPP1R14C Antibody

Target: PPP1R14C (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14C (PPP1R14C))

Binding Specificity: AA 133-163, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R14C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human and Mouse PP1R14C (C-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 133-163 amino acids from the C-terminal region of human PP1R14C.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PPP1R14C

Target: PPP1R14C (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14C (PPP1R14C))

Alternative Name: PPP1R14C (PPP1R14C Products)

Synonyms: CPI17-like antibody, KEPI antibody, NY-BR-81 antibody, 6330514J04Rik antibody, Kepi antibody, protein phosphatase 1 regulatory inhibitor subunit 14C antibody, protein phosphatase 1, regulatory (inhibitor) subunit 14c antibody, PPP1R14C antibody, Ppp1r14c antibody

Background: The degree of protein phosphorylation is regulated by a balance of protein kinase and phosphatase activities. Protein phosphatase-1 (PP1, see MIM 176875) is a signal-transducing phosphatase that influences neuronal activity, protein synthesis, metabolism, muscle contraction, and cell division. PPP1R14C is an inhibitor of PP1 (Liu et al., 2002 [PubMed 11812771]).[supplied by OMIM].Synonyms: KEPI, Kinase-enhanced PP1 inhibitor, NY-BR-81, PKC-potentiated PP1 inhibitory protein, Protein phosphatase 1 regulatory subunit 14C, Serologically defined breast cancer antigen NY-BR-81

Molecular Weight: 17843 Da

Gene ID: 81706

NCBI Accession: NP_112211