PLA2G7 antibody (Middle Region)

Catalog No. ABIN954165

Product Details anti-PLA2G7 Antibody

Target: PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))

Binding Specificity: AA 207-236, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G7 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody recognizes PLA2G7.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 207-236aa) of human PLA2G7.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PLA2G7

Target: PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))

Alternative Name: PLA2G7 (Lp-PLA2 Products)

Synonyms: LDL-PLA2 antibody, LP-PLA2 antibody, PAFAD antibody, PAFAH antibody, Lp-PLA2 antibody, PAF-AH antibody, R75400 antibody, zgc:77563 antibody, phospholipase A2 group VII antibody, phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) antibody, PLA2G7 antibody, Pla2g7 antibody, pla2g7 antibody

Background: The protein encoded by the PLA2G7 gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency.Synonyms: 1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycerophosphocholine esterase, Group-VIIA phospholipase A2, LDL-PLA2, LDL-associated phospholipase A2, PAF 2-acylhydrolase, PAF acetylhydrolase, PAFAH, Platelet-activating factor acetylhydrolase, gVIIA-PLA2

Gene ID: 7941

NCBI Accession: NP_001161829

Pathways: Peptide Hormone Metabolism