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PKD2 antibody (C-Term)
PKD2
Reactivity: Human, Mouse
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PKD2 Antibody
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Target
See all PKD2 Antibodies
PKD2
(Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
Binding Specificity
All epitopes for PKD2 antibodies
AA 873-903, C-Term
Reactivity
All reactivities for PKD2 antibodies
Human, Mouse
Host
All hosts for PKD2 antibodies
Rabbit
Clonality
All clonalities for PKD2 antibodies
Polyclonal
Conjugate
All conjugates for PKD2 antibodies
This PKD2 antibody is un-conjugated
Application
All applications for PKD2 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human and Mouse PKD2 (C-term).
Purification
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 873-903 amino acids from the C-terminal region of human PKD2
Isotype
Ig Fraction
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Discover our top product PKD2 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for PKD2
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Target
PKD2
(Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
Alternative Name
PKD2 (PKD2 Products )
Synonyms
APKD2 antibody, PC2 antibody, PKD4 antibody, Pc-2 antibody, TRPP2 antibody, C030034P18Rik antibody, RGD1559992 antibody, pkd2 antibody, trpp2 antibody, Cup antibody, PKD2L1 antibody, polycystin 2, transient receptor potential cation channel antibody, polycystic kidney disease 2 antibody, Polycystin-2 antibody, polycystin 2, transient receptor potential cation channel L homeolog antibody, PKD2 antibody, Pkd2 antibody, pkd-2 antibody, pkd2.L antibody, pkd2 antibody
Background
This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal dominant polycystic kidney disease.Synonyms: Autosomal dominant polycystic kidney disease type II protein, Polycystic kidney disease 2 protein, Polycystin-2, Polycystwin, R48321
Molecular Weight
109691 Da
Gene ID
5311
NCBI Accession
NP_000288
Pathways
cAMP Metabolic Process , Maintenance of Protein Location , Negative Regulation of Transporter Activity
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