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PITRM1 antibody (Middle Region)
PITRM1
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PITRM1 Antibody
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Target
See all PITRM1 Antibodies
PITRM1
(Pitrilysin Metallopeptidase 1 (PITRM1))
Binding Specificity
All epitopes for PITRM1 antibodies
AA 497-526, Middle Region
Reactivity
All reactivities for PITRM1 antibodies
Human
Host
All hosts for PITRM1 antibodies
Rabbit
Clonality
All clonalities for PITRM1 antibodies
Polyclonal
Conjugate
All conjugates for PITRM1 antibodies
This PITRM1 antibody is un-conjugated
Application
All applications for PITRM1 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Purification
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 497-526 amino acids from the Central region of human PITRM1
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for PITRM1
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Target
PITRM1
(Pitrilysin Metallopeptidase 1 (PITRM1))
Alternative Name
PITRM1 (PITRM1 Products )
Synonyms
MP1 antibody, PreP antibody, 2310012C15Rik antibody, AA410010 antibody, MP-1 antibody, Ntup1 antibody, mKIAA1104 antibody, PITRM1 antibody, wu:fa03d09 antibody, zgc:55469 antibody, pitrilysin metallopeptidase 1 antibody, pitrilysin metallepetidase 1 antibody, pitrilysin metallopeptidase 1 L homeolog antibody, PITRM1 antibody, Pitrm1 antibody, pitrm1.L antibody, pitrm1 antibody
Background
ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.Synonyms: KIAA1104, MP1, Metalloprotease 1, Pitrilysin metalloproteinase 1, Presequence protease mitochondrial
Molecular Weight
117455 Da
Gene ID
9606
Pathways
PI3K-Akt Signaling , SARS-CoV-2 Protein Interactome
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