Phosducin antibody (Middle Region)

Catalog No. ABIN954124

Product Details anti-Phosducin Antibody

Target: Phosducin (PDC)

Binding Specificity: AA 58-89, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phosducin antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human Phosducin / PDC (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 58-89 amino acids from the Central region of Human Phosducin / PDC.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Phosducin

Target: Phosducin (PDC)

Alternative Name: Phosducin / PDC (PDC Products)

Synonyms: MEKA antibody, PHD antibody, PhLOP antibody, PhLP antibody, Rpr-1 antibody, Rpr1 antibody, 33DPTP antibody, RPR1 antibody, phosducin antibody, PDC antibody, Pdc antibody

Background: This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.Synonyms: 33 kDa phototransducing protein, MEKA, PHD, PhLOP

Molecular Weight: 28246 Da

Gene ID: 5132

NCBI Accession: NP_002588