PEX14 antibody (Middle Region)

Catalog No. ABIN954097

Product Details anti-PEX14 Antibody

Target: PEX14 (Peroxisomal Biogenesis Factor 14 (PEX14))

Binding Specificity: AA 120-150, Middle Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX14 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human and Mouse Peroxin 14 / PEX14 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 120-150 amino acids from the Central region of Human Peroxin 14 / PEX14

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PEX14

Target: PEX14 (Peroxisomal Biogenesis Factor 14 (PEX14))

Alternative Name: Peroxin 14 / PEX14 (PEX14 Products)

Background: This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.Synonyms: PTS1 receptor-docking protein, Peroxin-14, Peroxisomal membrane protein PEX14

Molecular Weight: 41237 Da

Gene ID: 5195

NCBI Accession: NP_004556

Pathways: Maintenance of Protein Location