PCDHB14 antibody (N-Term)

Catalog No. ABIN954043

Product Details anti-PCDHB14 Antibody

Target: PCDHB14 (Protocadherin beta 14 (PCDHB14))

Binding Specificity: AA 165-193, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHB14 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects human PCDHB14 at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a protein A column; followed by peptide affinity purification.

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 165-193aa) of human PCDHB14.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PCDHB14

Target: PCDHB14 (Protocadherin beta 14 (PCDHB14))

Alternative Name: PCDHB14 (PCDHB14 Products)

Synonyms: PCDH-BETA14 antibody, 2210006M07Rik antibody, Pcdhb17 antibody, PcdhbN antibody, PCDHB14 antibody, protocadherin beta 14 antibody, protocadherin beta-14 antibody, PCDHB14 antibody, Pcdhb14 antibody, LOC487175 antibody, LOC100061546 antibody, LOC100353156 antibody

Background: The PCDHB14 gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.Synonyms: PCDH-beta-14, Protocadherin beta-14

Gene ID: 56122

NCBI Accession: NP_061757