PCDHA7 antibody (Middle Region)

Catalog No. ABIN954035

Product Details anti-PCDHA7 Antibody

Target: PCDHA7 (Protocadherin alpha 7 (PCDHA7))

Binding Specificity: AA 279-308, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHA7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detecs human PCDHA7 (Center).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a protein A column, followed by peptide affinity purification.

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 279-308 aa) of human PCDHA7.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PCDHA7

Target: PCDHA7 (Protocadherin alpha 7 (PCDHA7))

Alternative Name: PCDHA7 (PCDHA7 Products)

Synonyms: CNR4 antibody, CNRN4 antibody, CNRS4 antibody, CRNR4 antibody, PCDH-ALPHA7 antibody, Cnr4 antibody, Crnr4 antibody, rCNRv07 antibody, protocadherin alpha 7 antibody, PCDHA7 antibody, Pcdha7 antibody

Background: The PCDHA7 gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.Synonyms: CNRS4, PCDH-alpha-7, Protocadherin alpha-7

Gene ID: 56141

NCBI Accession: NP_061733