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KAT2B antibody (C-Term)
KAT2B
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-KAT2B Antibody
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Target
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KAT2B
(K(lysine) Acetyltransferase 2B (KAT2B))
Binding Specificity
All epitopes for KAT2B antibodies
AA 802-832, C-Term
Reactivity
All reactivities for KAT2B antibodies
Human
Host
All hosts for KAT2B antibodies
Rabbit
Clonality
All clonalities for KAT2B antibodies
Polyclonal
Conjugate
All conjugates for KAT2B antibodies
This KAT2B antibody is un-conjugated
Application
All applications for KAT2B antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody reacts to PCAF.
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Saturated Ammonium Sulfate (SAS) precipitation
Immunogen
KLH conjugated synthetic peptide between 802-832 amino acids from the C-terminal region of human PCAF
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS, 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for KAT2B
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Target
KAT2B
(K(lysine) Acetyltransferase 2B (KAT2B))
Alternative Name
PCAF / KAT2B (KAT2B Products )
Synonyms
PCAF antibody, pcaf antibody, si:ch211-1j13.2 antibody, zgc:161980 antibody, gb:dq017634 antibody, im:7156024 antibody, CAF antibody, P antibody, P/CAF antibody, A930006P13Rik antibody, AI461839 antibody, AW536563 antibody, Pcaf antibody, p/CAF antibody, lysine acetyltransferase 2B antibody, K(lysine) acetyltransferase 2B antibody, K(lysine) acetyltransferase 2A antibody, KAT2B antibody, kat2b antibody, kat2a antibody, Kat2b antibody
Background
CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.Synonyms: Histone acetylase PCAF, Histone acetyltransferase KAT2B, Histone acetyltransferase PCAF, Lysine acetyltransferase 2B, P/CAF, P300/CBP-associated factor
Molecular Weight
93013 Da
Gene ID
8850
NCBI Accession
NP_003875
Pathways
p53 Signaling , Regulation of Carbohydrate Metabolic Process
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