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PABPN1 antibody (C-Term)
PABPN1
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PABPN1 Antibody
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Target
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PABPN1
(Poly A Binding Protein Nuclear 1 (PABPN1))
Binding Specificity
All epitopes for PABPN1 antibodies
AA 269-298, C-Term
Reactivity
All reactivities for PABPN1 antibodies
Human
Host
All hosts for PABPN1 antibodies
Rabbit
Clonality
All clonalities for PABPN1 antibodies
Polyclonal
Conjugate
All conjugates for PABPN1 antibodies
This PABPN1 antibody is un-conjugated
Application
All applications for PABPN1 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human PABPN1 (C-term).
Purification
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 269-298 amino acids from the C-terminal region of human PABPN1
Isotype
Ig Fraction
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Discover our top product PABPN1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for PABPN1
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Target
PABPN1
(Poly A Binding Protein Nuclear 1 (PABPN1))
Alternative Name
PABPN1 (PABPN1 Products )
Synonyms
OPMD antibody, PAB2 antibody, PABII antibody, PABP-2 antibody, PABP2 antibody, Pabp3 antibody, mPABII antibody, ARABIDOPSIS POLY(A) BINDING 2 antibody, ATPAB2 antibody, F28A23.130 antibody, F28A23_130 antibody, POLY(A) BINDING PROTEIN 2 antibody, POLY(A)-BINDING PROTEIN 2 antibody, poly(A) binding protein 2 antibody, opmd antibody, pab2 antibody, pabp2 antibody, pabpii antibody, pabpn1 antibody, Pabpn1 antibody, Poly(A)-binding protein 2 antibody, fb19c03 antibody, wu:fb17e03 antibody, wu:fb18c06 antibody, wu:fb19c03 antibody, zgc:85979 antibody, zgc:92452 antibody, poly(A) binding protein nuclear 1 antibody, poly(A) binding protein, nuclear 1 antibody, poly(A) binding protein 2 antibody, poly(A) binding protein, nuclear 1 S homeolog antibody, poly(A) binding protein, nuclear 1 L homeolog antibody, polyadenylate-binding protein 2 antibody, poly(A) binding protein Pab2 antibody, PABPN1 antibody, Pabpn1 antibody, PAB2 antibody, pabpn1.S antibody, pabpn1.L antibody, LOC100728725 antibody, pab2 antibody, pabpn1 antibody
Background
This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails on the 3' ends of eukaryotic genes and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. An expansion of the trinucleotide (GCG) repeat from normal 6 to 8-13 at the 5' end of the coding region of this gene leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Multiple splice variants have been described but their full-length nature is not known. One splice variant includes introns 1 and 6 but no protein is formed.Synonyms: Nuclear poly(A)-binding protein 1, PAB2, PABP-2, PABP2, Poly(A)-binding protein 2, Polyadenylate-binding nuclear protein 1, Polyadenylate-binding protein 2
Molecular Weight
32749 Da
Gene ID
8106
NCBI Accession
NP_004634
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