Nyctalopin antibody (N-Term)

Catalog No. ABIN953798

Product Details anti-Nyctalopin Antibody

Target: Nyctalopin (NYX)

Binding Specificity: AA 59-89, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nyctalopin antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human Nyctalopin (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 59~89 amino acids from the N-terminal region of Human Nyctalopin. Genename: NYX

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Nyctalopin

Target: Nyctalopin (NYX)

Alternative Name: Nyctalopin (NYX Products)

Synonyms: MGC84276 antibody, CLRP antibody, CSNB1 antibody, CSNB1A antibody, CSNB4 antibody, NBM1 antibody, CLNP antibody, nob antibody, RGD1561300 antibody, nyctalopin antibody, nyctalopin L homeolog antibody, uncharacterized LOC491837 antibody, NYX antibody, nyx.L antibody, LOC491837 antibody, nyx antibody, Nyx antibody

Background: The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB. [provided by RefSeq].Synonyms: CLRP, NYX

Molecular Weight: 52000 Da

Gene ID: 60506

NCBI Accession: NP_072089