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NUMB antibody (N-Term)
NUMB
Reactivity: Human
WB, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NUMB Antibody
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Target
See all NUMB Antibodies
NUMB
(Numb Homolog (NUMB))
Binding Specificity
All epitopes for NUMB antibodies
AA 1-30, N-Term
Reactivity
All reactivities for NUMB antibodies
Human
Host
All hosts for NUMB antibodies
Rabbit
Clonality
All clonalities for NUMB antibodies
Polyclonal
Conjugate
All conjugates for NUMB antibodies
This NUMB antibody is un-conjugated
Application
All applications for NUMB antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human NUMB (N-term).
Purification
Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Immunogen
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human NUMB
Isotype
Ig Fraction
Top Product
Discover our top product NUMB Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for NUMB
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Target
NUMB
(Numb Homolog (NUMB))
Alternative Name
NUMB (NUMB Products )
Synonyms
C14orf41 antibody, S171 antibody, c14_5527 antibody, Nb antibody, NUMB, endocytic adaptor protein antibody, numb homolog (Drosophila) antibody, NUMB antibody, Numb antibody, numb antibody
Background
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene.Synonyms: Protein S171, Protein numb homolog, h-Numb
Molecular Weight
70804 Da
Gene ID
8650
NCBI Accession
NP_001005743
Pathways
Cell-Cell Junction Organization
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