MLXIPL antibody (C-Term)

Catalog No. ABIN953464

Product Details anti-MLXIPL Antibody

Target: MLXIPL (MLX Interacting Protein-Like (MLXIPL))

Binding Specificity: AA 623-653, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLXIPL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human MLXIPL (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 623-653 amino acids from the C-terminal region of human MLXIPL

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MLXIPL

Target: MLXIPL (MLX Interacting Protein-Like (MLXIPL))

Alternative Name: MLXIPL (MLXIPL Products)

Synonyms: ChREBP antibody, MLXIPL antibody, CHREBP antibody, MIO antibody, MONDOB antibody, WBSCR14 antibody, WS-bHLH antibody, bHLHd14 antibody, Wbscr14 antibody, MLX interacting protein-like antibody, MLX interacting protein like antibody, MLXIPL antibody, Mlxipl antibody

Background: This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.Synonyms: MIO, MLX-interacting protein-like, WBSCR14, WS basic-helix-loop-helix leucine zipper protein, Williams-Beuren syndrome chromosomal region 14 protein

Molecular Weight: 93073 Da

Gene ID: 51085

NCBI Accession: NP_116569

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process