H-2K antibody, H-2K(d) antibody, H2-K antibody, K-f antibody, histocompatibility 2, K1, K region antibody, H2-K1 antibody
Background
MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44 kDa) with beta2- microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. Lymphocytes are highly positive whereas fibroblasts or neurons show only a low level of antigen.Synonyms: H-2 class I histocompatibility antigen, H-2K(K), H2-K, H2-K1, K-K alpha chain