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MED16 antibody (Middle Region)
MED16
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MED16 Antibody
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Target
See all MED16 Antibodies
MED16
(Mediator Complex Subunit 16 (MED16))
Binding Specificity
All epitopes for MED16 antibodies
AA 252-281, Middle Region
Reactivity
All reactivities for MED16 antibodies
Human
Host
All hosts for MED16 antibodies
Rabbit
Clonality
All clonalities for MED16 antibodies
Polyclonal
Conjugate
All conjugates for MED16 antibodies
This MED16 antibody is un-conjugated
Application
All applications for MED16 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human MED16 (Center).
Purification
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 252-281 amino acids from the Central region of human MED16
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for MED16
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Target
MED16
(Mediator Complex Subunit 16 (MED16))
Alternative Name
MED16 (MED16 Products )
Synonyms
THRAP5 antibody, MED16 antibody, DRIP92 antibody, TRAP95 antibody, 95kDa antibody, A630083L04 antibody, Thrap5 antibody, Trap95 antibody, mediator complex subunit 16 antibody, mediator complex subunit 16 L homeolog antibody, MED16 antibody, Med16 antibody, med16.L antibody
Background
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.Synonyms: DRIP92, Mediator complex subunit 16, Mediator of RNA polymerase II transcription subunit 16, THRAP5, Thyroid hormone receptor-associated protein complex 95 kDa component, Vitamin D3 receptor-interacting protein complex component DRIP92
Molecular Weight
72kd
Gene ID
10025
NCBI Accession
NP_005472
Pathways
Intracellular Steroid Hormone Receptor Signaling Pathway , Nuclear Hormone Receptor Binding , Regulation of Lipid Metabolism by PPARalpha
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