ATF7IP2 antibody (Middle Region)

Catalog No. ABIN953344

Product Details anti-ATF7IP2 Antibody

Target: ATF7IP2 (Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2))

Binding Specificity: AA 325-355, Middle Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATF7IP2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human and Mouse MCAF2 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 325-355 amino acids from the Central region of human MCAF2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ATF7IP2

Target: ATF7IP2 (Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2))

Alternative Name: MCAF2 (ATF7IP2 Products)

Synonyms: MCAF2 antibody, 4930558K11Rik antibody, BC018510 antibody, Get-1 antibody, PSM2 antibody, activating transcription factor 7 interacting protein 2 antibody, ATF7IP2 antibody, Atf7ip2 antibody

Background: Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone 'Lys-9' trimethylation activity (Probable).Synonyms: ATF7IP2, Activating transcription factor 7-interacting protein 2

Molecular Weight: 75764 Da

Gene ID: 80063

NCBI Accession: NP_079273