LCA5L antibody (C-Term)

Catalog No. ABIN953157

Product Details anti-LCA5L Antibody

Target: LCA5L (Leber Congenital Amaurosis 5-Like (LCA5L))

Binding Specificity: AA 387-416, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LCA5L antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes LCA5L (C-term).

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 387-416 amino acids from the C-terminal region of Human LCA5L Genename: LCA5L

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for LCA5L

Target: LCA5L (Leber Congenital Amaurosis 5-Like (LCA5L))

Alternative Name: Lebercilin-Like Protein (LCA5L Products)

Synonyms: C21orf13 antibody, 4921526F01Rik antibody, Lcca5l antibody, Leber congenital amaurosis 5-like antibody, LCA5L, lebercilin like antibody, LCA5L antibody, Lca5l antibody

Background: Leber congenital amaurosis (LCA) is one of the most common causes of hereditary blindness or severe visual impairment in infants. Mutations in several genes with diverse functions mapping to two loci have been implicated in LCA causation. These proteins are involved in processes such as photoreceptor development and maintenance, phototransduction, vitamin A metabolism and protein trafficking. LCA5, also known as Lebercilin, is a ciliary protein that is widely expressed during development and localizes to the connecting cilia of photoreceptors and to the microtubules, centrioles and primary cilia of cultured mammalian cells. The Leber congenital amaurosis 5-like protein (LCA5L) is a 670 amino acid protein that belongs to the LCA5 family.Synonyms: C21orf13, LCA5L, Leber congenital amaurosis 5-like protein

Molecular Weight: 76505 Da

Gene ID: 150082

NCBI Accession: NP_689718