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KREMEN2 antibody (Middle Region)
KREMEN2
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-KREMEN2 Antibody
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Target
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KREMEN2
(Kringle Containing Transmembrane Protein 2 (KREMEN2))
Binding Specificity
All epitopes for KREMEN2 antibodies
AA 247-276, Middle Region
Reactivity
All reactivities for KREMEN2 antibodies
Human
Host
All hosts for KREMEN2 antibodies
Rabbit
Clonality
All clonalities for KREMEN2 antibodies
Polyclonal
Conjugate
All conjugates for KREMEN2 antibodies
This KREMEN2 antibody is un-conjugated
Application
All applications for KREMEN2 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody reacts to KREMEN2.
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Affinity chromatography on Protein A
Immunogen
KLH conjugated synthetic peptide between 247-276 amino acids from the Central region of human KREMEN2
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS, 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for KREMEN2
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Target
KREMEN2
(Kringle Containing Transmembrane Protein 2 (KREMEN2))
Alternative Name
Kremen Protein 2 (KREMEN2 Products )
Synonyms
krm2 antibody, KREMEN2 antibody, MGC147633 antibody, KRM2 antibody, 2900054E04Rik antibody, Krm2 antibody, kringle containing transmembrane protein 2 S homeolog antibody, kringle containing transmembrane protein 2 antibody, kremen2.S antibody, KREMEN2 antibody, kremen2 antibody, Kremen2 antibody
Background
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.Synonyms: Dickkopf receptor 2, KREMEN2, KRM2, Kringle domain-containing transmembrane protein 2, Kringle-containing protein marking the eye and the nose
Gene ID
79412
NCBI Accession
NP_078783
Pathways
WNT Signaling
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