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KCNA1 antibody (Middle Region)
KCNA1
Reactivity: Human
WB, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-KCNA1 Antibody
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Target
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KCNA1
(Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))
Binding Specificity
All epitopes for KCNA1 antibodies
AA 171-201, Middle Region
Reactivity
All reactivities for KCNA1 antibodies
Human
Host
All hosts for KCNA1 antibodies
Rabbit
Clonality
All clonalities for KCNA1 antibodies
Polyclonal
Conjugate
All conjugates for KCNA1 antibodies
This KCNA1 antibody is un-conjugated
Application
All applications for KCNA1 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human KCNA1 (Center).
Purification
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 171-201 amino acids from the Central region of human KCNA1
Isotype
Ig Fraction
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Discover our top product KCNA1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for KCNA1
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Target
KCNA1
(Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))
Alternative Name
KCNA1 (KCNA1 Products )
Synonyms
AEMK antibody, EA1 antibody, HBK1 antibody, HUK1 antibody, KV1.1 antibody, MBK1 antibody, MK1 antibody, RBK1 antibody, KCNA1 antibody, AI840627 antibody, Kca1-1 antibody, Kv1.1 antibody, Mk-1 antibody, Shak antibody, mceph antibody, Kcna antibody, Kcpvd antibody, potassium voltage-gated channel subfamily A member 1 antibody, potassium voltage-gated channel, shaker-related subfamily, member 1 antibody, fragile site, aphidicolin type, common, fra(12)(q24) antibody, KCNA1 antibody, Kcna1 antibody, FRA12E antibody
Background
This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).Synonyms: HBK1, HUKI, Potassium voltage-gated channel subfamily A member 1, Voltage-gated potassium channel subunit Kv1.1
Molecular Weight
56466 Da
Gene ID
3736
NCBI Accession
NP_000208
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