ITGA8 antibody (C-Term)

Catalog No. ABIN952914

Product Details anti-ITGA8 Antibody

Target: ITGA8 (Integrin alpha-8 (ITGA8))

Binding Specificity: AA 1032-1061, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human Integrin alpha-8 / ITGA8 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 1032-1061 amino acids from the C-terminal region of human ITGA8

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ITGA8

Target: ITGA8 (Integrin alpha-8 (ITGA8))

Alternative Name: Integrin alpha-8 / ITGA8 (ITGA8 Products)

Synonyms: AI447669 antibody, RGD1564327 antibody, integrin alpha 8 antibody, integrin subunit alpha 8 antibody, Itga8 antibody, ITGA8 antibody

Background: Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons.

Molecular Weight: 117474 Da

Gene ID: 8516

NCBI Accession: NP_003629