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INHBB antibody (C-Term)

INHBB Reactivity: Human, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN952903
  • Target See all INHBB Antibodies
    INHBB (Inhibin, beta B (INHBB))
    Binding Specificity
    • 10
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 376-404, C-Term
    Reactivity
    • 51
    • 37
    • 25
    • 14
    • 7
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 72
    • 11
    Rabbit
    Clonality
    • 73
    • 10
    Polyclonal
    Conjugate
    • 31
    • 20
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This INHBB antibody is un-conjugated
    Application
    • 68
    • 35
    • 31
    • 11
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes Human and Mouse INHBB (C-term).
    Characteristics
    Purified Ig fraction
    Purification
    Protein A column, followed by peptide affinity purification
    Immunogen
    KLH conjugated synthetic peptide between 376-404 amino acids from the C-terminal region of human INHBB
    Isotype
    Ig Fraction
    Top Product
    Discover our top product INHBB Primary Antibody
  • Application Notes
    Suggested dilutions:
    ELISA: 1/1000.
    Western Blot: 1/100-1/500.
    Immunohistochemistry on Paraffin Sections: 1/10-1/50.

    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Zhong, Pons, Poirier, Jiang, Liu, Sandusky, Shahda, Nakeeb, Schmidt, House, Ceppa, Zyromski, Liu, Jiang, Couch, Koniaris, Zimmers: "The systemic activin response to pancreatic cancer: implications for effective cancer cachexia therapy." in: Journal of cachexia, sarcopenia and muscle, Vol. 10, Issue 5, pp. 1083-1101, (2020) (PubMed).

  • Target
    INHBB (Inhibin, beta B (INHBB))
    Alternative Name
    Inhibin beta B Chain (INHBB) (INHBB Products)
    Synonyms
    actbb antibody, actbetaB antibody, inhibin antibody, inhibin, beta B antibody, inhibin beta B L homeolog antibody, inhibin beta B subunit antibody, inhibin beta B antibody, inhibin beta-B antibody, inhibin beta B chain antibody, inhbb antibody, inhbb.L antibody, INHBB antibody, Inhbb antibody, LOC100719829 antibody
    Background
    The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.Synonyms: Activin B, Activin beta-B chain
    Molecular Weight
    45122 Da
    Gene ID
    3625
    NCBI Accession
    NP_002184
    UniProt
    P09529
    Pathways
    Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
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