IMPDH1 antibody (N-Term)

Catalog No. ABIN952892

Product Details anti-IMPDH1 Antibody

Target: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Binding Specificity: AA 83-113, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IMPDH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human IMPDH1 / IMPD1 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 83-113 amino acids from the N-terminal region of Human IMPDH1 / IMPD1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IMPDH1

Target: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Alternative Name: IMPDH1 / IMPD1 (IMPDH1 Products)

Background: The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.Synonyms: IMP dehydrogenase 1, IMPD 1, IMPDH 1, IMPDH-1, IMPDH-I, Inosine-5'-monophosphate dehydrogenase 1

Molecular Weight: 55406 Da

Gene ID: 3614

NCBI Accession: NP_001136045

Pathways: Ribonucleoside Biosynthetic Process