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HYAL2 antibody (C-Term)

HYAL2 Reactivity: Human WB, FACS, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN952809
  • Target See all HYAL2 Antibodies
    HYAL2 (Hyaluronidase-2 (HYAL2))
    Binding Specificity
    • 15
    • 9
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 388-416, C-Term
    Reactivity
    • 58
    • 25
    • 5
    • 1
    • 1
    Human
    Host
    • 61
    • 2
    Rabbit
    Clonality
    • 63
    Polyclonal
    Conjugate
    • 19
    • 7
    • 7
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HYAL2 antibody is un-conjugated
    Application
    • 55
    • 32
    • 31
    • 13
    • 13
    • 13
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes Human HYAL2 / Hyaluronidase-2 (C-term).
    Purification
    Protein A column, followed by peptide affinity purification
    Immunogen
    KLH conjugated synthetic peptide between 388-416 amino acids from the C-terminal region of human HYAL2 / Hyaluronidase-2
    Isotype
    Ig Fraction
    Top Product
    Discover our top product HYAL2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    HYAL2 (Hyaluronidase-2 (HYAL2))
    Alternative Name
    HYAL2 / Hyaluronidase-2 (HYAL2 Products)
    Synonyms
    hyal2 antibody, hyal2b antibody, luca-2 antibody, luca2 antibody, xhyal2 antibody, si:dkey-42i9.14 antibody, hyal2a antibody, LUCA2 antibody, AI256841 antibody, AU020858 antibody, AW555733 antibody, oHyal2 antibody, hyaluronoglucosaminidase 2 S homeolog antibody, hyaluronoglucosaminidase 2 antibody, hyaluronoglucosaminidase 2b antibody, hyaluronoglucosaminidase 2 L homeolog antibody, hyal2.S antibody, HYAL2 antibody, hyal2b antibody, hyal2 antibody, hyal2.L antibody, Hyal2 antibody
    Background
    This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.Synonyms: Hyal-2, Hyaluronoglucosaminidase-2, LUCA2, Lung carcinoma protein 2
    Molecular Weight
    53860 Da
    Gene ID
    8692
    NCBI Accession
    NP_003764
    Pathways
    Transition Metal Ion Homeostasis, Glycosaminoglycan Metabolic Process
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