Histone 3 antibody
-
- Target See all Histone 3 (H3) Antibodies
- Histone 3 (H3)
-
Reactivity
- Human, Cow
-
Host
-
Sheep
-
Clonality
- Polyclonal
-
Conjugate
- This Histone 3 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity (Details)
-
Species reactivity (expected):Human.
Species reactivity (tested):Bovine. - Purification
- Protein G Chromatography
- Immunogen
- Intact Calf Histone H3 at 15.4 kD, 136 amino acids, complexed with RNA. Remarks: Calf Histone H3 has 100% identity to many other mammalian Histone H3 proteins.
- Isotype
- IgG
- Top Product
- Discover our top product H3 Primary Antibody
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Concentration
- 2.5 mg/mL
- Buffer
- PBS, pH 7.4
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store the antibody (in aliquots) at -20 °C.
-
- Target
- Histone 3 (H3)
- Alternative Name
- Histone H3 (H3 Products)
- Synonyms
- H-3 antibody, histocompatibility 3 antibody, H3 antibody
- Background
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.Synonyms: H3 Histone family, HIST1H3
-