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GSTa2 antibody (N-Term)

GSTa2 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN952640
  • Target See all GSTa2 Antibodies
    GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
    Binding Specificity
    • 14
    • 8
    • 7
    • 2
    • 1
    • 1
    AA 1-30, N-Term
    Reactivity
    • 38
    • 3
    • 1
    Human
    Host
    • 35
    • 4
    Rabbit
    Clonality
    • 37
    • 2
    Polyclonal
    Conjugate
    • 18
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GSTa2 antibody is un-conjugated
    Application
    • 32
    • 24
    • 18
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes Human GSTA2 / GST2 (N-term).
    Purification
    Protein A column, followed by peptide affinity purification
    Immunogen
    KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of Human GSTA2 / GST2.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GSTa2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
    Alternative Name
    GSTA2 / GST2 (GSTa2 Products)
    Synonyms
    GSTA1 antibody, GST2 antibody, GSTA2-2 antibody, GTA2 antibody, GTH2 antibody, Gsta1 antibody, Gst2-2 antibody, Gstc-2 antibody, Gstc2 antibody, glutathione S-transferase alpha 2 antibody, glutathione S-transferase antibody, glutathione S-transferase, alpha 2 (Yc2) antibody, GSTA2 antibody, Gsta2 antibody
    Background
    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.Synonyms: GST class-alpha member 2, GST-gamma, GSTA2-2, GTH2, Glutathione S-transferase A2, HA subunit 2
    Gene ID
    2939
    NCBI Accession
    NP_000837
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