GLRB antibody (N-Term)
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- Target See all GLRB Antibodies
- GLRB (Glycine Receptor, beta (GLRB))
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Binding Specificity
- AA 102-132, N-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GLRB antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- This antibody recognizes Human and Mouse Glycine receptor beta (N-term).
- Purification
- Protein A column, followed by peptide affinity purification
- Immunogen
- KLH conjugated synthetic peptide between 102-132 amino acids from the N-terminal region of Human Glycine receptor beta Genename: GLRB
- Isotype
- Ig Fraction
- Top Product
- Discover our top product GLRB Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- GLRB (Glycine Receptor, beta (GLRB))
- Alternative Name
- Glycine Receptor beta (GLRB Products)
- Background
- This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.Synonyms: GLRB, Glycine receptor 58 kDa subunit
- Molecular Weight
- 56122 Da
- Gene ID
- 2743
- NCBI Accession
- NP_000815
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