Glutathione Reductase antibody (C-Term)

Catalog No. ABIN952543

Product Details anti-Glutathione Reductase Antibody

Target: Glutathione Reductase (GSR)

Binding Specificity: AA 387-416, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutathione Reductase antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human Glutathione reductase (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 387-416 amino acids from the C-terminal region of human Glutathione reductase. Genename: GSR

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Glutathione Reductase

Target: Glutathione Reductase (GSR)

Alternative Name: Glutathione Reductase (GSR Products)

Synonyms: GR antibody, ATGR2 antibody, EMB2360 antibody, glutathione reductase antibody, AI325518 antibody, D8Ertd238e antibody, Gr-1 antibody, Gr1 antibody, DDBDRAFT_0168952 antibody, DDBDRAFT_0231410 antibody, DDB_0168952 antibody, DDB_0231410 antibody, 2151 antibody, CG2151 antibody, DTR antibody, Dm-TrxR antibody, DmTR antibody, DmTrx antibody, DmTrxR antibody, DmTrxR-1 antibody, Dmel\\CG2151 antibody, Gr antibody, Trx antibody, TrxR antibody, TrxR-1 antibody, Trxr1 antibody, anon-WO03040301.185 antibody, anon-WO03040301.187 antibody, dTrxR antibody, dmtrxr-1 antibody, gr antibody, l(1)G0154 antibody, l(1)G0379 antibody, l(1)G0477 antibody, l(1)G0481 antibody, trxr-1 antibody, gor1 antibody, glutathione reductase, gro-2 antibody, glutathione reductase antibody, glutathione-disulfide reductase antibody, GR; GRase antibody, mitochondrial glutathione reductase Pgr1 antibody, Glutathione reductase (GR) (GRase) antibody, Thioredoxin reductase-1 antibody, glutathione-disulfide reductase family protein antibody, glutathione reductase 1 antibody, GR antibody, gor antibody, GSR antibody, GSR1 antibody, Gsr_2 antibody, Gsr antibody, GSHR1 antibody, gsr antibody, LbGR antibody, pgr1 antibody, GSHR2 antibody, GLR2 antibody, Bcen_2392 antibody, RPE_1989 antibody, HCAG_02219 antibody, SJAG_01162 antibody, Trxr-1 antibody, PF14_0192 antibody, POPTR_0001s14480g antibody, gsr1 antibody

Background: This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.Synonyms: GLUR, GR, GRD1, GRase, GSR

Molecular Weight: 56257 Da

Gene ID: 2936

NCBI Accession: NP_000628

Pathways: Thyroid Hormone Synthesis, Cell RedoxHomeostasis