GLRX3 antibody (N-Term)

Catalog No. ABIN952537

Product Details anti-GLRX3 Antibody

Target: GLRX3 (Glutaredoxin 3 (GLRX3))

Binding Specificity: AA 88-118, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLRX3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects Glutaredoxin-3 / GLRX3 (N-term).

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 88-118 amino acids from the N-terminal region of human TXNL2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for GLRX3

Target: GLRX3 (Glutaredoxin 3 (GLRX3))

Alternative Name: Glutaredoxin-3 / GLRX3 (GLRX3 Products)

Synonyms: GLRX4 antibody, GRX3 antibody, GRX4 antibody, PICOT antibody, TXNL2 antibody, TXNL3 antibody, Txnl2 antibody, txnl2 antibody, wu:fb38e09 antibody, zgc:103648 antibody, NME/NM23 family member 9 antibody, thioredoxin-like 2 antibody, glutaredoxin 3 antibody, NME9 antibody, LOC100285323 antibody, GLRX3 antibody, Glrx3 antibody, glrx3 antibody

Background: GLRX3 is a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.Synonyms: GRX3, HUSSY-22, PICOT, PKC-interacting cousin of thioredoxin, PKC-theta-interacting protein, TXNL2, Thioredoxin-like protein 2

Gene ID: 10539

NCBI Accession: NP_001186797

Pathways: Cell RedoxHomeostasis