GGCX antibody (Middle Region)

Catalog No. ABIN952508

Product Details anti-GGCX Antibody

Target: GGCX (gamma-Glutamyl Carboxylase (GGCX))

Binding Specificity: AA 555-585, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GGCX antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human GGCX (Center).

Purification: Affinitty Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 555-585 amino acids from the Central region of Human GGCX

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GGCX

Target: GGCX (gamma-Glutamyl Carboxylase (GGCX))

Alternative Name: GGCX (GGCX Products)

Synonyms: GGCX antibody, cb751 antibody, si:ch1073-230p18.3 antibody, zgc:158736 antibody, ggcx antibody, GGC antibody, vkcfd1 antibody, CG13927 antibody, DgammaC antibody, Dmel\\CG13927 antibody, dGC antibody, dgammaC antibody, gammaC antibody, VKCFD1 antibody, gamma-glutamyl carboxylase antibody, gamma-glutamyl carboxylase L homeolog antibody, GGCX antibody, ggcx antibody, GC antibody, sce5891 antibody, ggcx.L antibody, Ggcx antibody

Background: This gene encodes an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: GC, Gamma-glutamyl carboxylase, Vitamin K gamma glutamyl carboxylase, Vitamin K-dependent gamma-carboxylase

Molecular Weight: 87561 Da

Gene ID: 2677

NCBI Accession: NP_000812

Pathways: SARS-CoV-2 Protein Interactome