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GRPR antibody (Middle Region)

GRPR Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN952465
  • Target See all GRPR Antibodies
    GRPR (Gastrin-Releasing Peptide Receptor (GRPR))
    Binding Specificity
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 130-160, Middle Region
    Reactivity
    • 42
    • 14
    • 12
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 42
    • 1
    • 1
    Rabbit
    Clonality
    • 43
    • 1
    Polyclonal
    Conjugate
    • 21
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This GRPR antibody is un-conjugated
    Application
    • 19
    • 17
    • 14
    • 8
    • 7
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody recognizes Human Gastrin-releasing peptide receptor (Center).
    Purification
    Protein A column, followed by peptide affinity purification
    Immunogen
    KLH conjugated synthetic peptide between 130~160 amino acids from the Central region of Human Gastrin-releasing peptide receptor Genename: GRPR
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GRPR Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    GRPR (Gastrin-Releasing Peptide Receptor (GRPR))
    Alternative Name
    Gastrin-Releasing Peptide Receptor (GRPR Products)
    Synonyms
    GRPR antibody, GRP-R antibody, gastrin releasing peptide receptor antibody, GRPR antibody, Grpr antibody
    Background
    Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.Synonyms: GRP-R, GRP-preferring bombesin receptor, GRPR
    Molecular Weight
    43199 Da
    Gene ID
    2925
    NCBI Accession
    NP_005305
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