Galectin 10 antibody (C-Term)

Catalog No. ABIN952434

Product Details anti-Galectin 10 Antibody

Target: Galectin 10 (CLC) (Charcot-Leyden Crystal Protein (CLC))

Binding Specificity: AA 90-119, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Galectin 10 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to CLC.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 90-119 amino acids from the C-terminal region of human CLC

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Galectin 10

Target: Galectin 10 (CLC) (Charcot-Leyden Crystal Protein (CLC))

Alternative Name: Galectin-10 (CLC Products)

Background: Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias.Synonyms: CLC, Charcot-Leyden crystal protein, EC=3.1.1.5, Eosinophil lysophospholipase, Galectin10, LGALS10, Lysolecithin acylhydrolase

Molecular Weight: 16481 Da

Gene ID: 1178

NCBI Accession: NP_001819

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response