FDPS antibody (N-Term)

Catalog No. ABIN952387

Product Details anti-FDPS Antibody

Target: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Binding Specificity: AA 53-82, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FDPS antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to FDPS.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 53-82 amino acids from the N-terminal region of human FDPS

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FDPS

Target: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Alternative Name: FPP Synthetase (FDPS Products)

Synonyms: CG12389 antibody, DmFPPS antibody, DmFPPSase antibody, DmFPS antibody, Dmel\\CG12389 antibody, FPS antibody, fpps antibody, fps antibody, l(2)k06103 antibody, v(2)k03514 antibody, NCU01175.1 antibody, 16.m00760 antibody, DDBDRAFT_0206220 antibody, DDBDRAFT_0215017 antibody, DDB_0206220 antibody, DDB_0215017 antibody, FPPS antibody, Ac2-125 antibody, (2E antibody, 6030492I17Rik antibody, AI256750 antibody, Fdpsl1 antibody, mKIAA1293 antibody, Farnesyl pyrophosphate synthase antibody, farnesyl diphosphate synthase antibody, farnesyl diphosphate synthase L homeolog antibody, farnesyl pyrophosphate synthase antibody, farnesyl pyrophosphate synthetase antibody, farnesyl-pyrophosphate synthetase antibody, FDP synthase antibody, Farnesyl pyrophosphate synthetase antibody, farnesyl diphosphate synthetase antibody, farnesyl pyrophosphate synthase 1 antibody, Fpps antibody, fdps antibody, fdps.L antibody, MGG_08649 antibody, TP03_0857 antibody, Tb09.160.4300 antibody, fpp antibody, BBOV_I000120 antibody, fps antibody, fpps antibody, FDPS antibody, Fdps antibody, fps1 antibody

Background: This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: FDPS, FPS, Farnesyl diphosphate synthase, Farnesyl pyrophosphate synthetase, KIAA1293

Molecular Weight: 48275 Da

Gene ID: 2224

NCBI Accession: NP_001129293

Pathways: Regulation of Muscle Cell Differentiation