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FGFRL1 antibody (N-Term)

FGFRL1 Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN952316
  • Target See all FGFRL1 Antibodies
    FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))
    Binding Specificity
    • 15
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 51
    • 13
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 52
    • 1
    • 1
    Rabbit
    Clonality
    • 52
    • 2
    Polyclonal
    Conjugate
    • 19
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FGFRL1 antibody is un-conjugated
    Application
    • 42
    • 22
    • 21
    • 13
    • 13
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to FGFRL1.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography on Protein A
    Immunogen
    The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product FGFRL1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS, 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))
    Alternative Name
    FGFRL1 (FGFRL1 Products)
    Synonyms
    fgfrl1 antibody, zgc:64084 antibody, FGFR5 antibody, FGFR5beta antibody, FGFR5gamma antibody, Fgfr5 antibody, FHFR antibody, XFGFRL1 antibody, Xndk antibody, fgfrl1-a antibody, fgfrl1-b antibody, ndk antibody, im:7154242 antibody, fibroblast growth factor receptor like 1a antibody, fibroblast growth factor receptor-like 1 antibody, fibroblast growth factor receptor like 1 antibody, fibroblast growth factor receptor like 1 L homeolog antibody, fibroblast growth factor receptor like 1b antibody, fgfrl1a antibody, Fgfrl1 antibody, FGFRL1 antibody, fgfrl1.L antibody, fgfrl1b antibody
    Background
    Synonyms: FGF homologous factor receptor, FGFR-like protein, FGFR5, FHFR, Fibroblast growth factor receptor 5, Fibroblast growth factor receptor-like 1
    Molecular Weight
    54537 Da
    Gene ID
    53834
    NCBI Accession
    NP_001004356
    Pathways
    RTK Signaling
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