RGD1560480 antibody, fezf antibody, znf312b antibody, MGC145310 antibody, FEZ antibody, ZNF312B antibody, 3110069A13Rik antibody, Fez antibody, Zfp312-like antibody, fez-like antibody, fez antibody, fezf2 antibody, wu:fc29c05 antibody, wu:fc89h05 antibody, zgc:153730 antibody, Fez family zinc finger 1 antibody, FEZ family zinc finger 1 antibody, Fez family zinc finger protein 1 antibody, FEZ family zinc finger 1 S homeolog antibody, Fezf1 antibody, FEZF1 antibody, fezf1 antibody, Tsp_12536a antibody, Tsp_12536 antibody, fezf1.S antibody
Background
Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors. FEZF1 is expressed in brain. Little or no expression in other tissues. Overexpressed specifically in gastric cancers. A 2-to 20-fold increase is found in over 50 % of gastric cancer tissues. Subcellular location of FEZF1 is in the nucleus.Synonyms: FEZ, Fez family zinc finger protein 1, ZNF312B, Zinc finger protein 312B