EXTL2 antibody (C-Term)

Catalog No. ABIN952146

Product Details anti-EXTL2 Antibody

Target: EXTL2 (Exostoses (Multiple)-Like 2 (EXTL2))

Binding Specificity: AA 280-310, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXTL2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human and Mouse EXTL2 (C-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 280~310 amino acids from the C-terminal region of human EXTL2.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for EXTL2

Target: EXTL2 (Exostoses (Multiple)-Like 2 (EXTL2))

Alternative Name: Exostosin-Like 2 (EXTL2 Products)

Synonyms: 3000001D04Rik antibody, AW146439 antibody, EXTR2 antibody, exostoses (multiple)-like 2 antibody, exostosin like glycosyltransferase 2 antibody, exostosin-like glycosyltransferase 2 antibody, Extl2 antibody, EXTL2 antibody

Background: EXTL2 is a glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.Synonyms: 4-N-acetylhexosaminyltransferase EXTL2, Alpha-1, Alpha-GalNAcT EXTL2, EXT-related protein 2, EXTR2, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase

Molecular Weight: 37466 Da

Gene ID: 2135

NCBI Accession: NP_001028197