EME2 antibody (C-Term)

Catalog No. ABIN952075

Product Details anti-EME2 Antibody

Target: EME2 (Essential Meiotic Endonuclease 1 Homolog 2 (EME2))

Binding Specificity: AA 248-278, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EME2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes EME2 at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 248-278aa) of human EME2.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for EME2

Target: EME2 (Essential Meiotic Endonuclease 1 Homolog 2 (EME2))

Alternative Name: EME2 (EME2 Products)

Synonyms: RGD1304924 antibody, 2810013J18Rik antibody, SLX2B antibody, gs125 antibody, essential meiotic structure-specific endonuclease subunit 2 antibody, Eme2 antibody, EME2 antibody

Background: EME2 forms a heterodimer with MUS81 (MIM 606591) that functions as an XPF (MIM 278760)-type flap/fork endonuclease in DNA repair [Ciccia et al., 2007, PubMed 17289582].Synonyms: Probable crossover junction endonuclease

Gene ID: 197342

NCBI Accession: NP_001010865